Friday, June 8

PART I - TRANSCRIPTION

Chair: D. Tenen (Harvard Medical School, Boston, USA)

• MECHANISTIC INSIGHTS INTO EARLY CHROMATIN PRIMING EVENTS IN HEMATOPOIETIC STEM CELLS
  C. Bonifer (St James's University Hospital, Leeds, United Kingdom)
• THE CONTROL OF TRANSCRIPTION FACTOR DOSAGES IN DEVELOPMENT AND CANCER
  F. Rosenbauer (Max Delbrück Center for Molecular Medicine, Berlin, Germany)
• EVOLUTION OF A BLOOD STEM CELL ENHANCER
  B. Göttgens (School of Clinical Medicine, Cambridge, United Kingdom)
• UNIQUE AML SUBTYPES BY INTEGRATED MOLECULAR APPROACHES R. Delwel (Erasmus Medical Center, Rotterdam, The Netherlands) K ROLE OF THE MEF2C TRANSCRIPTION FACTOR IN MYELOID CELL FATE AND LEUKEMIA
  C. Stocking (Heinrich-Pette-Institut, Hamburg, Germany)
• DECIPHERING JUNB TRANSCRIPTION NETWORK IN HEMATOPOIETIC STEM CELLS
  E. Passegue (University of California, San Francisco, USA)

PART II - REGULATION OF NORMAL AND LEUKEMIC STEM CELLS

Chair: T. Enver (Weatherall Institute of Molecular Medicine, Oxford, United Kingdom)

• AGING AND SENESCENCE OF HEMATOPOIETIC STEM CELLS
  G. de Haan (University Medical Center, Groningen, The Netherlands)
• LYMPHOID CELLS AS LEUKEMIC STEM CELLS IN ACUTE MYELOID LEUKEMIA? INSIGHTS FROM THE MURINE CALM-AF10 LEUKEMIA MODEL
  C. Buske (GSF-National Research Center for Environment and Health, Munich, Germany)
• ROLE OF PROTEIN KINASE B (PKB/c-akt) IN REGULATING HEMAPOIETIC CELL FATE DECISIONS
  C. Eaves (BC Cancer Research Center, Vancouver, Canada)
• DIFFERENTIAL CELL SIGNALLING IN HEALTHY AND LEUKEMIC B CELLS DELINEATED BY GENE EXPRESSION OVER TIME
  J. Gribben (St. Bartholomew`s and The Royal London Hospital, London, United Kingdom)
• REGULATION OF HEMAPOIETIC STEM CELLS BY THE SMAD SIGNALLING PATHWAY
  G. Karlsson (University of Lund, Lund, Sweden)
• UNEXPECTED NOTCH FUNCTION IN THE YOLK SAC ERYTHROID CELLS
  A. Bigas (Institut de Recerca Oncologica, Barcelona, Spain)

PART III - SIGNAL TRANSDUCTION

Chair: I. Touw (Erasmus MC, Rotterdam, The Netherlands)

• MUTANT JAK2 AND CYTOKINE RECEPTOR ROUTING IN MPD
  S. Constantinescu (Ludwig Institute for Cancer Research, Brussels, Belgium)
• ROLE OF PROTEIN KINASE B (PKB/c-AKT) IN REGULATING HEMATOPOIETIC CELL FATE DECISIONS
  P. Coffer (University Medical Center, Utrecht, The Netherlands)
• FLT3-ITD SIGNALING IN AML
  H. Serve (Hematology and Oncology University Hospital Munster, Munster, Germany)
• TARGETING CALCINEURIN ACTIVATION AS A THERAPEUTIC STRATEGY FOR LYMPHOID MALIGNANCIES
  J. Ghysdael (Institut Curie, CNRS UMR146, Orsay, France)
• SCF-DEPENDENT CONTROL OF mRNA TRANSLATION IN ERYTHROPOIESIS
  M. von Lindern (Erasmus MC, Rotterdam, The Netherlands)
• MECHANISMS OF EPO RECEPTOR DOWNREGULATION
  F. Verdier (Institut Cochin, Paris, France)