Education Session Friday June 16

EDUCATION SESSION

08.00 - 09.30 hours, Room: Auditorium
14.15 - 15.45 hours, Room: Forum

ACUTE MYELOID LEUKEMIA
Chair: H. Dombret (Hôpital Saint-Louis, Paris, France)
SIGNALLING PATHWAYS TARGETED BY MOLECULAR THERAPY IN ACUTE MYELOID LEUKEMIA
Dr. Brian Huntly (Brigham and Women's Hospital, Boston, USA)
ANTIBODY DIRECTED CHEMOTHERAPY IN ACUTE MYELOID LEUKEMIA
A.K. Burnett (University Hospital of Wales, Cardiff, United Kingdom)
EMERGING THERAPIES FOR OLDER ADULTS WITH ACUTE MYELOID LEUKEMIA
S. Amadori (Tor Vergata University Hospital, Rome, Italy)

EDUCATION SESSION

08.00 - 09.30 hours and 14.15 - 15.45 hours, Room: Y

CHRONIC MYELOID LEUKEMIA
Chair: G. Martinelli (Institute of Hematology and Medical Oncology“Seràgnoli”, Bologna, Italy)
MOLECULAR BASIS OF RESISTANCE TO IMATINIB
J. Melo (Imperial College London, London, United Kingdom)
UPDATE OF FIRST LINE IMATINIB TREATMENT IN CHRONIC-PHASE CHRONIC MYELOID LEUKEMIA
F. Guilhot (University Hospital CHU La Milétrie, Poitiers, France)
ROLE OF ALLOGENEIC STEM CELL TRANSPLANTATION FOR CHRONIC MYELOID LEUKEMIA
A. Gratwohl (University of Basel, Basel, Switzerland)

EDUCATION SESSION

08.00 - 09.30 hours and 16.00 - 17.30 hours, Room: Forum

MYELODYSPLASTIC SYNDROMES
Chair: M. Cazzola (University of Pavia Medical School, Pavia, Italy)
MOLECULAR PATHOGENESIS OF THE MYELODYSPLASTIC SYNDROMES, INCLUDING THE 5Q- SYNDROME
J. Boultwood (John Radcliffe Hospital, Oxford, United Kingdom)
EPIDEMIOLOGY AND CLINICAL OUTCOME
A. Giagounidis (St. Johannes Hospital, Duisburg, Germany)
NOVEL TREATMENT STRATEGIES FOR MYELODYSPLASTIC SYNDROMES
M. Cazzola (University of Pavia Medical School, Pavia, Italy)

EDUCATION SESSION

08.00 - 09.30 hours and 14.15 - 15.45 hours, Room: A

DIAGNOSIS OF HEMATOLOGICAL MALIGNANCIES
Chair: A. Orfao (University of Salamanca, Salamanca, Spain)
GENE EXPRESSION PROFILING IN ACUTE MYELOID LEUKEMIA
L. Bullinger (University of Ulm, Ulm, Germany)
DIAGNOSIS OF HEMATOLOGICAL MALIGNANCIES: NEW APPLICATIONS FOR FLOW CYTOMETRY
A. Orfao (University of Salamanca, Salamanca, Spain)
ESTABLISHING A REGIONAL HEMATO-ONCOLOGY DIAGNOSTIC SERVICE
W.N. Erber (Addenbrooke’s Hospital, Cambridge, United Kingdom)

EDUCATION SESSION

08.00 - 09.30 hours and 16.00 - 17.30 hours, Room: X

MYELOPROLIFERATIVE DISORDERS
Chair: T. Barbui (Ospedali Riuniti Bergamo, Bergamo, Italy)
IDIOPATHIC ERYTHROCYTOSIS: DIFFERENTIAL DIAGNOSIS AND MANAGEMENT
G. Finazzi (Ospedali Riuniti di Bergamo, Bergamo, Italy)
MANAGEMENT OF PREGNANCY IN POLYCYTHEMIA VERA AND ESSENTIAL THROMBOCYTHEMIA
J.J. Kiladjian (Hopital Avicenne, Bobigny, France)
RECENT CLINICAL TRIALS IN POLYCYTHEMIA VERA AND ESSENTIAL THROMBOCYTHEMIA
P.J. Campbell (Cambridge Institute for Medical Research, Cambridge, United Kingdom)

EDUCATION SESSION

08.00 - 09.30 hours and 16.00 - 17.30 hours, Room: B

ANEMIA
Chair: D. Loukopoulos (Foundation of Biomedical Research, Athens, Greece)
HEPCIDIN – THE PRINCIPLE REGULATOR OF SYSTEMIC IRON METABOLISM
E. Nemeth (UCLA, David Geffen School of Medicine, Los Angeles, USA)
PATHOGENESIS AND MANAGEMENT OF IRON-LOADING ANEMIAS
A. Piga (University of Turin, Turin, Italy)
ANEMIA OF CHRONIC DISEASE
J. Kushner (University of Utah Medical Center, Salt Lake City, USA)

EDUCATION SESSION

08.00 - 09.30 hours and 14.15 - 15.45 hours, Room: L

CONGENITAL PRELEUKEMIC SYNDROMES
Chair: A. Biondi (M. Tettamanti Research Center, Monza, Italy)
DOWN SYNDROME AS A MODEL FOR ANEUPLOIDY IN LEUKEMIA
S. Izraeli (Sheba Medical Center, Tel-Hashomer, Israel)
FANCONI'S ANEMIA: GENOMIC INSTABILITY LEADING TO APLASTIC ANEMIA AND CANCER PREDISPOSITION
D. Williams (Cincinnati Children's Hospital Medical Center, Cincinnati, USA)
DYSKERATOSIS CONGENITA: A CANCER PRONE SYNDROME ASSOCIATED WITH TELOMERASE DEFICIENCY
I. Dokal (Hammersmith Hospital, London, United Kingdom)

EDUCATION SESSION

09.45 - 11.15 hours, Room: Forum
14.15 - 15.45 hours, Room: Room X

CHRONIC LYMPHOCYTIC LEUKEMIA
Chair: G.A. Pangalis (National and Kapodistrian University of Athens, Athens, Greece)
THE CELL OF ORIGIN OF CHRONIC LYMPHOCYTIC LEUKEMIA
M. Ferrarini (National Insitute for Cancer Research, Genova, Italy)
CHRONIC LYMPHOCYTIC LEUKEMIA: GENETICS FOR PREDICTING OUTCOME
S. Stilgenbauer (University of Ulm, Ulm, Germany)
TREATMENT STRATIFICATION, NOVEL TREATMENT STRATEGIES AND END-POINTS OF THERAPY
P. Hillmen (Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom)

EDUCATION SESSION

08.00 - 09.30 hours and 14.15 - 15.45 hours, Room: C

ERYTHROCYTE ENZYME ABNORMALITIES AND DISEASE
Chair: E. Beutler (The Scripps Research Institute, La Jolla, USA)
THE CLINICIANS’ APPROACH TO THE DIAGNOSIS OF ENZYME DEFICIENCIES OF RED BLOOD CELLS
E. Beutler (The Scripps Research Institute, La Jolla, USA)
PYRUVATE KINASE DEFICIENCY: GENOTYPE TO PHENOTYPE
W.W. van Solinge (University Medical Center Utrecht, Utrecht, The Netherlands)
GLUCOSE 6-PHOSPHATE DEHYDROGENASE DEFICIENCY: GENOTYPE TO PHENOTYPE
L. Luzzatto (University of Genova, Genova, Italy)

EDUCATION SESSION

09.45 - 11.15 hours, Room: X
16.00 - 17.30 hours, Room: Auditorium

NON-HODGKIN'S LYMPHOMA
Chair: A. Hagenbeek (Academic Medical Center, Amsterdam,
The Netherlands)
CLINICAL IMPACT OF GENE EXPRESSION PROFILING IN AGGRESSIVE LYMPHOMA
A. Rosenwald (University of Würzburg, Würzburg, Germany)
RESPONSE CRITERIA IN MALIGNANT LYMPHOMAS REVISITED - A PROPOSAL OF THE INTERNATIONAL HARMONIZATION PROJECT OF THE GERMAN COMPETENCE NETWORK OF MALIGNANT LYMPHOMAS
B. Pfistner (University Hospital of Cologne, Cologne, Germany)
TREATMENT OF DIFFUSE LARGE B-CELL LYMPHOMA
M. Pfreundschuh (Medical University Saarland, Homburg, Germany)

EDUCATION SESSION

09.45 - 11.15 hours and 14.15 - 15.45 hours, Room: Auditorium

MULTIPLE MYELOMA
Chair: P. Sonneveld (Erasmus Medical Center, Rotterdam,
The Netherlands)
PROGNOSTIC FACTORS FOR MULTIPLE MYELOMA
J. Drach (Medical University of Vienna, Vienna, Austria)
TREATMENT OF ELDERLY MYELOMA PATIENTS
M. Boccadoro (San Giovanni Battista Hospital, Turin, Italy)
NOVEL DRUGS FOR MULTIPLE MYELOMA
J.F. San Miguel (University of Salamanca, Salamanca, Spain)

EDUCATION SESSION

09.45 - 11.15 hours and 16.00 - 17.30 hours, Room: Y

ACUTE LYMPHOBLASTIC LEUKEMIA
Chair: D. Hoelzer (University of Frankfurt, Frankfurt, Germany)
CLINICAL IMPACT OF PHARMACOGENETICS AND MICROARRAY STUDIES IN ALL
M. Schrappe (University Hospital Kiel, Kiel, Germany)
ACUTE LYMPHOBLASTIC LEUKEMIA: THERAPEUTIC STRATEGIES IN CHILDREN AND ADOLESCENTS REVISITED
R. Pieters (Erasmus MC – Sophia Children’s Hospital, Rotterdam, The Netherlands)
THERAPY OF ADULT ALL ACCORDING TO PROGNOSTIC FACTORS AND MRD
D. Hoelzer (University of Frankfurt, Frankfurt, Germany)

EDUCATION SESSION

09.45 - 11.15 hours and 16.00 - 17.30 hours, Room: A

THROMBOSIS
Chair: I. Pabinger (Medical University Vienna, Vienna, Austria)
NEW CONCEPTS OF THE ANTIPHOSPHOLIPID SYNDROME
Ph. de Groot (University Medical Center Utrecht, Utrecht, The Netherlands)
DIAGNOSIS AND TREATMENT OF PULMONARY EMBOLISM
V. Pengo (University of Padova, Padova, Italy)
LOW MOLECULAR WEIGHT HEPARIN AS ANTITUMOR AGENTS
A. Lee (McMaster University, Hamilton, Canada)

EDUCATION SESSION

09.45 - 11.15 hours and 16.00 - 17.30 hours, Room: C

CELLULAR IMMUNOTHERAPY
Chair: F. Stevenson, University of Southampton, Southampton, United Kingdom
NK CELL BIOLOGY: RELEVANCE OF "MISSING SELF RECOGNITION” AND OTHER ASPECTS OF BASIC NK CELL BIOLOGY FOR CLINICAL APPROACHES
K. Kärre (Karolinska Institute, Stockholm, Sweden)
DENDRITIC CELL IMMUNOTHERAPY: PROMISE AND CHALLENGES
M. Dhodapkar (The Rockefeller University, New York, USA)
FROM TUMOR-SPECIFIC T CELLS TO THERAPEUTIC T CELL RECEPTORS
M. Theobald (Johannes Gutenberg University, Mainz, Germany)

EDUCATION SESSION

09.45 - 11.15 hours and 14.15 - 15.45 hours, Room: B

HODGKIN'S LYMPHOMA
Chair: M. Björkholm (Karolinska University, Stockholm, Sweden)
TREATMENT OF STAGE I AND II HODGKIN'S LYMPHOMA
J. Raemaekers (Radboud University Medical Centre, Nijmegen, The Netherlands)
NEW APPROACHES FOR ADVANCED-STAGE AND RELAPSED DISEASE
A. Engert (University Hospital of Cologne, Cologne, Germany)
LATE TOXICITY IN PATIENTS TREATED FOR HODGKIN'S LYMPHOMA
B. Aleman (The Netherlands)

EDUCATION SESSION

09.45 - 11.15 hours and 16.00-17.30 hours, Room: L

HEMOSTASIS
Chair: R. Schneppenheim (University Medical Center Hamburg - Eppendorf, Hamburg, Germany)
VON WILLEBRAND DISEASE: THE 80TH ANNIVERSARY
P.M. Mannucci (A. Bianchi Bonomi Center, Milan, Italy)
BRIDGING OF ANTICOAGULATION DURING INVASIVE PROCEDURES
S. Schulman (McMaster University, Hamilton, Canada)
PREDICTING DISSEMINATED INTRAVASCULAR COAGULATION IN THE INTENSIVE CARE UNIT
C.E. Dempfle (University of Heidelberg, Mannheim, Germany)